Evaluation of computed tomography findings in patients with Covid-19

Mohaya Farzin

Abstract


Due to the Covid 19 pandemic and the lack of useful information, in this study, we evaluated the High-resolution computed tomography ( HRCT )of patients with Covid 19.92 patients confirmed by RT_PCR in Razi Hospital in Rasht were included in the study.  In addition to their demographic and clinical information, their  HRCT  findings were collected for evaluation. Among 92 patients (47 men, 45 women), the earliest symptoms included cough 81.5%, fever 67.4%, and muscle pain 58.7% Six patients required intubation and mechanical ventilation at some point during their hospital stay. The most common  HRCT  findings in our study were grade 4, peripheral lesion 87%, bilateral 95.7%, mixed 76.08%, Ground-glass opacity (GGOs) 75%, left lower lobe 94.56%. Among 92 patients, we had some inconsistent findings including two patients with cardiomegaly, three patients with pleural effusion, and bilateral pleural effusion in only one patient. Compared to other studies, it can be concluded that peripheral, bilateral, mixed, GGOs, left lower lobe involvement are important findings in most patients with covid 19. We suspect that the disease has more severe lung involvement in men and less involvement in women, which needs further investigation.


Keywords


Covid 19, High-Resolution Computed Tomography, clinical

References


Kannan S, Shaik Syed Ali P, Sheeza A, Hemalatha K. COVID-19 (Novel Coronavirus 2019) - recent trends. European review for medical and pharmacological sciences. 2020;24(4):2006-11.

Sun J, He WT, Wang L, Lai A, Ji X, Zhai X, et al. COVID-19: Epidemiology, Evolution, and Cross-Disciplinary Perspectives. Trends in molecular medicine. 2020;26(5):483-95.

Nikolich-Zugich J, Knox KS, Rios CT, Natt B, Bhattacharya D, Fain MJ. SARS-CoV-2 and COVID-19 in older adults: what we may expect regarding pathogenesis, immune responses, and outcomes. GeroScience. 2020;42(2):505-14.

Li X, Geng M, Peng Y, Meng L, Lu S. Molecular immune pathogenesis and diagnosis of COVID-19. Journal of pharmaceutical analysis. 2020;10(2):102-8.

Pascarella G, Strumia A, Piliego C, Bruno F, Del Buono R, Costa F, et al. COVID-19 diagnosis and management: a comprehensive review. Journal of internal medicine. 2020;288(2):192-206.

Sachs JD, Horton R, Bagenal J, Amor YB, Caman OK, Lafortune G. The Lancet COVID-19 Commission. The Lancet. 2020;396(10249):454-5.

Singhal T. A Review of Coronavirus Disease-2019 (COVID-19). Indian journal of pediatrics. 2020;87(4):281-6.

Esakandari H, Nabi-Afjadi M, Fakkari-Afjadi J, Farahmandian N, Miresmaeili SM, Bahreini E. A comprehensive review of COVID-19 characteristics. Biological procedures online. 2020;22:19.

Guo YR, Cao QD, Hong ZS, Tan YY, Chen SD, Jin HJ, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak - an update on the status. Military Medical Research. 2020;7(1):11.

Chakraborty C, Sharma AR, Sharma G, Bhattacharya M, Lee SS. SARS-CoV-2 causing pneumonia-associated respiratory disorder (COVID-19): diagnostic and proposed therapeutic options. European review for medical and pharmacological sciences. 2020;24(7):4016-26.

Brauner M, Grenier P, Mompoint D, Lenoir S, De Cremoux H. Pulmonary sarcoidosis: evaluation with high-resolution CT. Radiology. 1989;172(2):467-71.

Shan F, Gao Y, Wang J, Shi W, Shi N, Han M, et al. Lung infection quantification of COVID-19 in CT images with deep learning. arXiv preprint arXiv:200304655. 2020.

Montalbo FJ. Truncating fined-tuned vision-based models to lightweight deployable diagnostic tools for SARS-CoV-2 infected chest X-rays and CT-scans. Multimedia Tools and Applications. 2022.

Raghuvanshi V, Sood RG, Jhobta A, Sarkar M, Tomar A, Khanna S. Use of High-Resolution Computed Tomography (HRCT) in Diagnosis of Sputum Negative Pulmonary Tuberculosis. Turkish thoracic journal. 2016;17(2):59-64.

Gao L, Zhang J. Pulmonary High-Resolution Computed Tomography (HRCT) Findings of Patients with Early-Stage Coronavirus Disease 2019 (COVID-19) in Hangzhou, China. Medical science monitor : international medical journal of experimental and clinical research. 2020;26:e923885.

Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med. 2020;382(8):727-33.

Majidi H, Bani-Mostafavi ES, Mardanshahi Z, Godazandeh F, Ghasemian R, Heydari K, et al. High-resolution computed tomography finding in 552 patients with symptomatic COVID-19: first report from north of Iran. Emergency radiology. 2020;27(6):633-9.

Dai H, Zhang X, Xia J, Zhang T, Shang Y, Huang R, et al. High-resolution Chest CT Features and Clinical Characteristics of Patients Infected with COVID-19 in Jiangsu, China. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 2020;95:106-12.

Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020;382(18):1708-20.

Chen Z, Fan H, Cai J, Li Y, Wu B, Hou Y, et al. High-resolution computed tomography manifestations of COVID-19 infections in patients of different ages. European journal of radiology. 2020;126:108972.

Zamanian M, Foroozanfar Z, Izadi Z, Jafari S, Derakhshankhah H, Salimi M, et al. Association of Underlying Diseases and Clinical Characteristics with Mortality in Patients with 2019 Novel Coronavirus in Iran. Arch Clin Infect Dis. 2020;15(5):e104621.

Chakraborty C, Sharma A, Sharma G, Bhattacharya M, Lee S. SARS-CoV-2 causing pneumonia-associated respiratory disorder (COVID-19): diagnostic and proposed therapeutic options. Eur Rev Med Pharmacol Sci. 2020;24(7):4016-26.

Bai HX, Hsieh B, Xiong Z, Halsey K, Choi JW, Tran TML, et al. Performance of Radiologists in Differentiating COVID-19 from Non-COVID-19 Viral Pneumonia at Chest CT. Radiology. 2020;296(2):E46-e54.

Muhammad SZ, Ahmed A, Shahid I, Khalid A, Menezes RG, Sheikh MU, et al. Chest computed tomography findings in hospitalized COVID-19 patients: a systematic review and meta-analysis. Le infezioni in medicina. 2020;28(3):295-301.


Refbacks

  • There are currently no refbacks.


Copyright (c) 2023 Mohaya Farzin

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.