Investigating the frequency of skin manifestation in newborns admitted to a Children's Hospital in the North of Iran

Hojat Eftekhari, Faranak Poorsaravani, Sadroddin Mahdipour, Sareh Shafaei, Haleh Masoudi, Anahita Shabani


Skin manifestations, a common problem in infants, can be a serious concern for parents. Most manifestations are benign and transient, but some of them need more evaluation regarding whether they can negatively affect infant health. In this study, it is aimed to evaluate the frequency of skin manifestation in newborns admitted to the department of newborns and NICU from 2019 to 2020. This cross-sectional was performed on infants hospitalized in the department of pediatrics and NICU of a pediatric hospital in Guilan, Iran, from 2019 to 2020. The sampling was performed using the census method. The information was gathered using a checklist of infant and mother characteristics. Out of 323 newborns, 164 cases had skin lesions (50.8%). The lesions of Erythema toxicum, Cutis marmorata, Diaper dermatitis, Milia, salmon patch, and Mongolian spots were presented at 14.9%, 9.9%, 8.1%, 5.6%, 4.3%, and 2.8%, respectively. Only 5.38% of infants required treatment. There was no significant relationship between skin lesions and demographic factors of gestational age, type of delivery, or the family history of dermatological diseases. The rate of skin lesions was moderate to high in hospitalized newborns. In addition, Erythema toxicum, Cutis marmorata, Diaper dermatitis, Salmon patch, and Mongolian spots were more prevalent in infants. These findings can help pediatric physicians effectively in their early diagnosis and therapeutic procedures.


Skin lesions; Newborn; NICU; Erythema toxicum

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Haveri FT, Inamadar AC. A cross-sectional prospective study of cutaneous lesions in newborn. ISRN Dermatol. 2014; 2014:360590.

Techasatian L, Sanaphay V, Paopongsawan P, Schachner LA. Neonatal Birthmarks: A Prospective Survey in 1000 Neonates. Glob Pediatr Health. 2019; 6:2333794x19835668.

Jain N, Rathore BS, Agarwal AK, Bhardwaj A. Cutaneous lesions in neonates admitted in a tertiary setup neonatal intensive care unit. Indian J Paediatr Dermatol. 2013; 14(3):62-6.

O'Connor NR, McLaughlin MR, Ham P. Newborn skin: Part I. Common rashes. Am Fam Physician. 2008; 77(1):47-52.

Magin PJ, Adams J, Pond CD, Smith W. Topical and oral CAM in acne: a review of the empirical evidence and a consideration of its context. Complement Ther Med. 2006; 14(1):62-76.

Ben-Gashir MA, Seed PT, Hay RJ. Are quality of family life and disease severity related in childhood atopic dermatitis? J Eur Acad Dermatol Venereol. 2002; 16(5):455-62.

Golchie J, Ramezanpoor A. Prevalence of contagious skin diseases in Rasht Lakan prison. J Guilan Univ Med Sci. 2003; 11(44):9-13.

Malekzad F, Rahmati M, Taheri A. Prevalence of skin diseases among nursing home patients in elderly home nursings in North of Tehran. Pajoohandeh J. 2007; 12(3):253-8.

Soleymani-Ahmadi M, Safa O, Zare S. Prevalence of scabies in soldiers of Bandar Abbas air force base, 2001. Hormozgan Med J. 2002; 6(1):15-9.

Ansarin H, Abbasi Moin S. Prevalence of pruritic skin diseases in elderly persons living in Kahrizak Institute in Tehran in first half of 1379. Iran J Dermatol. 2001; 5(1):34-8.

Abbott MB, Vlasses CH. Nelson textbook of pediatrics. JAMA. 2011;306(21):2387–2388.

Weiner GM, Zaichkin J; American Academy of Pediatrics; American Heart Association. Textbook of Neonatal Resuscitation (NRP), 7th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2016.

Abkenar MJ, Mojen LK, Shakeri F, Varzeshnejad M. Skin Injuries and its Related Factors in the Neonatal Intensive Care Unit. Iran J Neonatol. 2020; 11(4):93-8.

Firouzi H, Jalalimehr I, Ostadi Z, Rahimi S. Cutaneous Lesions in Iranian Neonates and Their Relationships with Maternal-Neonatal Factors: A Prospective Cross-Sectional Study. Dermatol Res Pract. 2020; 2020:8410165.

Reginatto FP, DeVilla D, Muller FM, Peruzzo J, Peres LP, Steglich RB, et al. Prevalence and characterization of neonatal skin disorders in the first 72h of life. J Pediatr (Rio J). 2017; 93(3):238-45.

Gupta D, Thappa DM. Mongolian spots--a prospective study. Pediatr Dermatol. 2013; 30(6):683-8.

Gupta D, Thappa DM. Mongolian spots. Indian J Dermatol Venereol Leprol. 2013; 79(4):469-78.

Hosseinabad M. A review of cutaneous manifestations in newborn infants. Der Pharm Lett. 2017; 9:1-8.

Reza AM, Farahnaz GZ, Hamideh S, Alinaghi SA, Saeed Z, Mostafa H. Incidence of Mongolian spots and its common sites at two university hospitals in Tehran, Iran. Pediatr Dermatol. 2010; 27(4):397-8.

Maher MK, Abady SH, Tabrizi A. Salmon patch and Mongolian spot frequency in the northwest of Iran: a descriptive study. Iran J Neonatol. 2016; 7(3):24-8.

Khoshnevisasl P, Sadeghzadeh M, Mazloomzadeh S, Zanjani AA. The incidence of birthmarks in neonates born in Zanjan, Iran. J Clin Neonatol. 2015; 4(1):8-12.

Ábrahám R, Meszes A, Gyurkovits Z, Bakki J, Orvos H, Csoma ZR. Cutaneous lesions and disorders in healthy neonates and their relationships with maternal-neonatal factors: a cross-sectional study. World J Pediatr. 2017; 13(6):571-6.

Giuffrida R, Borgia F, De Pasquale L, Guarneri F, Cacace C, Cannavò SP. Skin lesions in preterm and term newborns from Southern Italy and their relationship to neonatal, parental and pregnancy-related variables. G Ital Dermatol Venereol. 2019; 154(4):400-4.

Shajari H, Shajari A, Habiby NSM. The incidence of birthmarks in Iranian neonates. Acta Medica Iranica. 1970; 45(5):424-426.



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