Clinical characteristics and laboratory findings of patients with COVID-19 in Rasht, Iran

Tofigh Yaghubi Kalurazi, Vahid Shakoori, Sara Nasiri, Ali Alavi Foumani, Ezat Hesni, Lida Mahfoozi, Dorrin Aghajani, Zahra Gholamalipour, Roxana Ehsani, Samaneh Mirzaei Dahka, Niloofar Faraji


In December 2019, an epidemic of an unknown respiratory virus emerged in Wuhan, China, and put the whole world in crisis; a newly emerged coronavirus, called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We aimed to evaluate epidemiological and clinical characteristics of coronavirus disease 2019 (COVID-19) patients in the North of Iran. We extracted demographics and baseline clinical characteristics from 126 patients with polymerase chain reaction (PCR) confirmed COVID-19 in Razi Hospital, Rasht, Iran. The mean age of patients was 62 years, ranging from 28 to 92 years old. Overall, 57.1% of cases were male and 42.9% were female. Totally, 17.5% of patients had direct contact with a SARS-CoV-2 infected patient. The most common underlying diseases were diabetes (11.9%) and cardiovascular disease (CVD) (7.1%). The mean±SD of lactate dehydrogenase (LDH), creatine phosphokinase (CPK), creatine kinase MB (CK-MB), serum glutamic oxaloacetic transaminase (SGOT), and erythrocyte sedimentation rate (ESR) were remarkably higher than the normal range, (1231±866.4 U/L, 766.8±2288.6 U/L, 59.28±55.1 U/L, 112.28±213 U/L and 67.61±31 mm/hr), respectively. Also, the average O2 Saturation (O2Sat) was 61.4±26.3%. Male gender, advanced age, a higher level of the cardiac enzyme, and a lower level of O2Sat are associated with severity in COVID-19 patients. 


SARS-CoV-2; COVID-19; Laboratory findings

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