The sound of getting rid of coronavirus by RNA interference technology: RNAi against COVID-19

Ali Ahmadi; Hamed Hekmatnezhad

doi:10.52547/JCBioR.1.2.45

Authors

Ali Ahmadi Faculty of Biological Sciences and Technologies, Sari Branch, Islamic Azad University, Sari, Iran
Hamed Hekmatnezhad Department of Basic Sciences, Sari Agricultural Sciences and Natural Resources University, Sari, Iran https://orcid.org/0000-0002-5716-9240

DOI:

https://doi.org/10.52547/JCBioR.1.2.45

Keywords:

RNA interference, siRNA, COVID-19, SARS-CoV-2

Abstract

No Abstract.

Author Biography

Hamed Hekmatnezhad, Department of Basic Sciences, Sari Agricultural Sciences and Natural Resources University, Sari, Iran

References

Chen Y, Liu Q, Guo D. Emerging coronaviruses: Genome structure, replication, and pathogenesis. J Med Virol. 2020; 92(4):418-23.

Lundstrom K. Coronavirus Pandemic-Therapy and Vaccines. Biomedicines. 2020; 8(5).

Lu R, Zhao X, Li J, Niu P, Yang B, Wu H, et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet. 2020; 395(10224):565-74.

Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W, et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature. 2020; 579(7798):270-3.

Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G, et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr. 2020; 9(1):51-60. 6. Zhang Y, Li T, Fu L, Yu C, Li Y, Xu X, et al. Silencing SARS-CoV Spike protein expression in cultured cells by RNA interference. FEBS Lett. 2004; 560(1-3):141-6.

Kurreck J. RNA interference: from basic research to therapeutic applications. Angew Chem Int Ed Engl. 2009; 48(8):1378-98.

Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs. Genes Dev. 2001; 15(2):188-200.

Zamore PD, Tuschl T, Sharp PA, Bartel DP. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell. 2000; 101(1):25-33.

Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, et al. Substrate-specific structural rearrangements of human Dicer. Nat Struct Mol Biol. 2013; 20(6):662-70.

- Shi Y. Mammalian RNAi for the masses. Trends Genet. 2003; 19(1):9-12.

Déctor MA, Romero P, López S, Arias CF. Rotavirus gene silencing by small interfering RNAs. EMBO Rep. 2002; 3(12):1175-80.

Ge Q, McManus MT, Nguyen T, Shen CH, Sharp PA, Eisen HN, et al. RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci U S A. 2003; 100(5):2718-23.

Coburn GA, Cullen BR. Potent and specific inhibition of human immunodeficiency virus type 1 replication by RNA interference. J Virol. 2002; 76(18):9225-31.

Martínez MA, Clotet B, Esté JA. RNA interference of HIV replication. Trends Immunol. 2002; 23(12):559-61.