Identification of bacterial isolates from nasolacrimal duct infection in children with congenital nasolacrimal duct obstruction from Feiz teaching hospital, Isfahan

Helma Ebneali, Fereshteh Saffari, Alireza Zandi, Jamshid Faghri

Abstract


Dacryocystitis is a lacrimal sac and duct inflammation. It can be inherited or congenital. Two primary forms are acquired dacryocystitis, acute and chronic. The goal of this study is to recognize common bacteria causing nasolacrimal duct infection in children with congenital nasolacrimal duct obstruction and to determine their antimicrobial susceptibility profiles. This cross-sectional research was conducted from January to February 2017 in the Department of Ophthalmology affiliated to Isfahan University of Medical Sciences (center of Iran). Using phenotypic and genotypic approaches, identification of specimens was performed. Disc diffusion method was used for checking antibiotic susceptibility. All of the 59 isolates from the culture of specimens belonged to Gram-positive cocci. Staphylococcus epidermidis was the predominant species (n= 44, 74.6%) followed by Staphylococcus aureus (n= 11, 18.6%), Staphylococcus haemolyticus (n= 2, 3.4%) and each of Staphylococcus saprophyticus, and Streptococcus pneumoniae (n= 1, 1.7%). Totally, the highest resistance was found against erythromycin and tetracycline while, chloramphenicol, and ciprofloxacin showed the highest susceptibility. The current research is useful in evaluating the suitable antibiotic in our area for the systemic treatment of dacryocystitis. The most effective agents against the most common isolates were chloramphenicol and ciprofloxacin. Since the bacteriology of nasolacrimal duct infections varies from region to region, it is recommended that further studies in other areas of our country can be detected the etiology of bacterial pathogens involved in acute infections.


Keywords


Dacryocystitis; Antibiotic resistance; Congenital nasolacrimal duct obstruction; Bacteriology

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