Case reports in the use of vitamin C based regimen in prophylaxis and management of COVID-19 among Nigerians

Goodluck A. K. Ohanube, Uchejeso M. Obeta, Chinaza R. Ikeagwulonu


This case study was based on the novel opinion that daily intake of vitamin C can serve as a prophylactic and curative intervention for the coronavirus disease of 2019 (COVID-19) via homeostatic and epigenetic mechanisms. To substantiate this hypothesis, some Nigerians who used vitamin C based regimen consented to share their experience in the prevention and management of the coronavirus irrespective of their country of abode. Participants all agreed to the use of their information for the public, albeit anonymous, via appending their signatures on an informed consent form. The documented cases took place from March 15 to September 1, 2020, this was to allow for more time to be able to observe the participants. The study provided evidence that regular use of Ascorbic acid tablets and vitamin C enriched plants could improve the immunity needed against the infection of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).


COVID-19; Ascorbic acid; Vitamin C; Epigenetics; Homeostasis; Coronavirus


Carr AC. Vitamin C in pneumonia and sepsis. In: Chen Q, Vissers M, editors. Vitamin C: New Biochemical and Functional Insights. Oxidative Stress and Disease. Boca Raton, FL CRC Press/Taylor & Francis; 2020. p. 115-35.

Hemilä H. A brief history of vitamin C and its deficiency, Scurvy [Thesis]. University of Helsinki. 2006. Available at:

World Health Organization and Food and Agriculture Organization of the United Nations. 2004. Vitamin and mineral requirements in human nutrition. Retrieved July 8, 2020. Available at:

World Health Organization. Transmission of SARS-CoV-2: implications for infection prevention precautions: scientific brief. Retrieved July 9 2020. Available at:

Jahan I, Onay A. Potentials of plant-based substance to inhabit and probable cure for the COVID-19. Turk J Biol. 2020; 44(3):228-41.

Mirzaie A, Halaji M, Dehkordi FS, Ranjbar R, Noorbazargan H. A narrative literature review on traditional medicine options for treatment of corona virus disease 2019 (COVID-19). Complement Ther Clin Pract. 2020; 40:101214.

Nandedkar MA, Mahajan SV, Pardeshi KM, Oswal RJ, Shah MS. Novel perception on the anti-viral effect of bioactive natural molecules against COVID -19. World J Pharm Res. 2020; 9(7): 674-96.

Figueroa-Méndez R, Rivas-Arancibia S. Vitamin C in Health and Disease: Its Role in the Metabolism of Cells and Redox State in the Brain. Front Physiol. 2015; 6:397.

Carr AC, Maggini S. Vitamin C and Immune Function. Nutrients. 2017; 9(11).

Akbari A, Jelodar G, Nazifi S, Sajedianfard J. An Overview of the Characteristics and Function of Vitamin C in Various Tissues: Relying on its Antioxidant Function. Zahedan J Res Med Sci. 2016; 18(11):e4037.

Przybyło M, Langner M. On the physiological and cellular homeostasis of ascorbate. Cell Mol Biol Lett. 2020; 25:32.

Anuraag, B. A mathematical model showing the potential of vitamin C to boost the innate immune response. Open J Math Sci. 2019; 3:245-55.

Ohanube Goodluck AK, Uchejeso OM. COVID-19: Novel Opinion on Strategic Prophylaxis and Cure Using Vitamin C (Ascorbic Acid). Act Sci Nutr Health. 2020; 4(5): 32-3.

Bharara A, Grossman C, Grinnan D, Syed A, Fisher B, DeWilde C, et al. Intravenous Vitamin C Administered as Adjunctive Therapy for Recurrent Acute Respiratory Distress Syndrome. Case Rep Crit Care. 2016; 2016:8560871.

Ohanube GAK, Obeta MU, Ikeagwulonu RC, and Jwanse IR. COVID-19: A Case Study of Using Vitamin C Enriched Plants and Ascorbic Acid as Cure. Am J Med Case Rep. 2020; 8(11): 435-37.

Premium Times. How I recovered from coronavirus – Seyi Makinde. April 6, 2020. Retrieved July 8, 2020. Available at:

The Nation. What I did after testing positive for COVID-19 – UCH CMD. April 12, 2020. Retrieved July 9, 2020. Available at:

Vanguard. BREAKING: UCH Chief, Prof. Otegbayo, tests negative for coronavirus. April 2, 2020. Retrieved July 9, 2020, Available at:

Total Coronavirus Cases in Nigeria. Retrieved August 26, 2020. Available at:

Total Coronavirus Cases in Germany. Retrieved August 26, 2020. Available at:


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