Pathophysiological evaluation of venous catheter infections in hemodialysis patients

Hossein Abbaspour Firozjah, Seyed Masaod Hashemi Karouei, Ayatollah Nasrollahi Omran

Abstract


Central venous catheters (CVC) for blood withdrawal and return to dialysis is a method commonly applied. The increasing use of CVC and following that complications arising from the use of these catheters is more critical. Therefore, this study aimed to investigate and determine the microbiological characteristics of bloodstream infection caused by intravascular device catheters. The study included 87 patients with chronic renal failure, with venous catheters and with or without infection in the age group over ten years for hemodialysis patients referred to Shahid Beheshti hospital in Babol, the North of Iran. Bacterial isolation and identification were carried out using standard microbiological and biochemical techniques. Of the 87 hemodialysis patients, 77 patients received hemodialysis three times a week, eight patients twice a week and two patients received hemodialysis only twice a year. In this study, out of 87 patients undergoing hemodialysis, 60 (69%) samples had positive cultures. Of which, 56 bacterial isolates (64.4%), and 4 (5%) fungal samples were isolated. The most obtained isolates were coagulase-negative staphylococci (23%) and the least episode was Escherichia coli (2%). In addition, all patients with fungal infections (candidiasis) also had diabetes. In conclusion, our study showed that the most common cause of bloodstream infection among patients was bacterial and S. saprophyticus was more common than others. This practical study helped us to understand the effect of using catheters for patients who had an emergency and were unable to reach a blood vessel for hemodialysis. 


Keywords


Hemodialysis; Intravenous catheter; Bacterial infection; Blood cultures

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