Pathophysiological evaluation of venous catheter infections in hemodialysis patients

Hosein Abbaspour Firozjah, Masaod Hashem, Ayatollah Nasrollahi Omran


The use of central venous catheters (CVC) for blood withdrawal and return to dialysis is a method commonly applied. With increasing use of CVC, complications arising from the use of these catheters was more important. The most common complication is infection. Therefore, the aim of this study was to investigate and determine the microbiological characteristics of bloodstream infection caused by intravascular device catheters in the north of Iran.

The study included 87 patients with chronic renal failure, with venous catheter and with or without signs of infection in the age group over 10 years for hemodialysis referred to Shahid Beheshti Hospital in Babol. Bacterial isolation and identification were carried out using standard microbiological and biochemical techniques.

A total 87 hemodialysis patients, 77 patients received hemodialysis three times a week, 8 patients twice a week and two patients received hemodialysis only twice a year. From 87 hemodialysis patients studied, 43 (49%) were male and 44 (51%) were female. In this study, out of 87 patients undergoing hemodialysis, 56 bacterial strains (64.4%) were taken from the patient's two-line Chaldean catheter blood sample and 4 (5%) Candida samples were isolated. The most obtained isolates were S. saprophyticus (23%) and the least episode was E. coli (2%) (Table 3). In addition, all patients with fungal infections (candidiasis) also had diabetes.

In conclusion our study showed that the most common cause of bloodstream infection among patients with bacterial and S. saprophyticus were more common than others. This practical study helped us to understand the effect of using catheters for patients who had an emergency and were unable to reach a blood vessel for hemodialysis.


hemodialysis, intravenous catheter, bacteria, blood cultures.



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