An overview of nanoparticle production from plant gums and their action as antimicrobial agents
Abstract
There have been various chemicals and routines for the treatment of infections. The extensive use of antibiotics has led to serious issues including antibiotic resistance and serious side effects. The use of plant gum nanoparticles (NPs) is one of the several ways that can be employed greatly for the treatment of infections and have gained so much popularity by the scientists recently due to their several advantages over chemicals including being nontoxic and providing better tolerance to the patient. Several studies have been performed recently, stressing the undeniable advantages of these substances in the treatment of illnesses compared with their chemical counterparts. There are studies suggesting that these NPs have great potential in the treatment of multi-drug-resistant bacteria and that these substances have great anti-cancer effects due to their anti-inflammatory roles. Among various plant gums, Gum Arabia, gum Karaya, Kondagogu gum, and gum Tragacanth, Guar gum, and gum Ghatti have gathered more interest as anti-inflammatory subjects for studies because of their several pros including having more tissue bio-availability, being easy to use, etc. The use of plant gums can be limited due to a series of disadvantages but this can be untangled by using natural nanoparticles which can be synthesized via several ways including ultrasonic irradiation, etc. Among various metallic NPs, the most frequent of them in these studies are Silver nanoparticles (AgNPs) and Gold nanoparticles (AuNPs). According to these studies, AgNPs have a more bactericidal effect than AuNPs which is due to them being more of an antioxidant.
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Ventola CLJP, therapeutics. The antibiotic resistance crisis: part 1: causes and threats. 2015; 40(4):277-83.
Mansury D, Motamedifar M, Sarvari J, Shirazi B, Khaledi A. Antibiotic susceptibility pattern and identification of extended spectrum β-lactamases (ESBLs) in clinical isolates of Klebsiella pneumoniae from Shiraz, Iran. Iran J Microbiol. 2016; 8(1):55-61.
Siddiqui AH, Koirala J. Methicillin Resistant Staphylococcus aureus. StatPearls [internet]. 2020.
Motamedifar M, Sarai HSE, Mansury D. Patterns of constitutive and inducible clindamycin resistance in Staphylococcus aureus isolated from clinical samples by D-test method, shiraz, southwest of Iran. Galen Med J. 2014; 3(4):216-21.
Levitus M, Rewane A, Perera TB. Vancomycin-Resistant Enterococci. 2023. In: StatPearls [Internet].
Bassetti M, Peghin M, Vena A, Giacobbe DRJFim. Treatment of infections due to MDR Gram-negative bacteria. Front Med (Lausanne). 2019; 6:74.
Tanhaeian A, Damavandi MS, Mansury D, Ghaznini K. Expression in eukaryotic cells and purification of synthetic gene encoding enterocin P: a bacteriocin with broad antimicrobial spectrum. AMB Express. 2019; 9(1):6.
Islam NU, Amin R, Shahid M, Amin M, Zaib S, Iqbal J. A multi-target therapeutic potential of Prunus domestica gum stabilized nanoparticles exhibited prospective anticancer, antibacterial, urease-inhibition, anti-inflammatory and analgesic properties. BMC Complement Altern Med. 2017; 17(1):1-17.
Deps PD, Nasser S, Guerra P, Simon M, Birshner RDC, Rodrigues LC. Adverse effects from multi-drug therapy in leprosy: a Brazilian study. Lepr Rev. 2007; 78(3):216-22.
Iravani S. Plant gums for sustainable and eco-friendly synthesis of nanoparticles: recent advances. Inorg Nano-Met Chem. 2020; 50(6):469-88.
Anwar A, Masri A, Rao K, Rajendran K, Khan NA, Shah MR, et al. Antimicrobial activities of green synthesized gums-stabilized nanoparticles loaded with flavonoids. Sci Rep. 2019; 9(1):1-12.
Sharma G, Kalra SK, Tejan N, Ghoshal U. Nanoparticles based therapeutic efficacy against Acanthamoeba: Updates and future prospect. Exp Parasitol. 2020; 218:108008.
Escárcega-González CE, Garza-Cervantes JA, Vazquez-Rodríguez A, Montelongo-Peralta LZ, Treviño-Gonzalez MT, Castro EDB, et al. In vivo antimicrobial activity of silver nanoparticles produced via a green chemistry synthesis using Acacia rigidula as a reducing and capping agent. Int J Nanomed. 2018; 13:2349.
Huang J, Lin L, Sun D, Chen H, Yang D, Li Q. Bio-inspired synthesis of metal nanomaterials and applications. Chem Soc Rev. 2015; 44(17):6330-74.
Darroudi M, Yazdi MET, Amiri MS. Plant-mediated biosynthesis of nanoparticles. 21st century nanoscience–A handbook: CRC Press; 2020. p. 1---18.
Hashemzadeh MR, Yazdi MET, Amiri MS, Mousavi SH. Stem cell therapy in the heart: Biomaterials as a key route. Tissue Cell. 2021:101504.
Khan I, Saeed K, Khan I. Nanoparticles: Properties, applications and toxicities. Arab J Chem. 2019; 12(7):908-31.
Amiri MS, Mohammadzadeh V, Yazdi MET, Barani M, Rahdar A, Kyzas GZ. Plant-Based Gums and Mucilages Applications in Pharmacology and Nanomedicine: A Review. Molecules. 2021; 26(6):1770.
Bhosale RR, Osmani RAM, Moin A. Natural gums and mucilages: a review on multifaceted excipients in pharmaceutical science and research. Int J Pharmacogn Phytochem Res. 2014; 15(4):901-12.
Abulafatih H. Medicinal plants in southwestern Saudi Arabia. Econ Bot. 1987; 41(3):354-60.
Rastogi A, Zivcak M, Sytar O, Kalaji HM, He X, Mbarki S, et al. Impact of metal and metal oxide nanoparticles on plant: a critical review. Front Chem. 2017; 5:78.
Mansury D, Ghazvini K, Jamehdar SA, Badiee A, Tafaghodi M, Nikpoor AR, et al. Increasing cellular immune response in liposomal formulations of DOTAP encapsulated by fusion protein Hspx, PPE44, and Esxv, as a potential tuberculosis vaccine candidate. Rep Biochem Mol Bio. 2019; 7(2):156.
Patra JK, Das G, Fraceto LF, Campos EVR, del Pilar Rodriguez-Torres M, Acosta-Torres LS, et al. Nano based drug delivery systems: recent developments and future prospects. J Nanobiotechnology. 2018; 16(1):1-33.
Padil VV, Zare EN, Makvandi P, Černík M. Nanoparticles and nanofibres based on tree gums: Biosynthesis and applications. Compr Anal Chem. 2021. p. 223-65.
Mirhosseini H, Amid BT. A review study on chemical composition and molecular structure of newly plant gum exudates and seed gums. Food Res Int. 2012; 46(1):387-98.
Mahfoudhi N, Chouaibi M, Donsi F, Ferrari G, Hamdi S. Chemical composition and functional properties of gum exudates from the trunk of the almond tree (Prunus dulcis). Food Sci Technol Int. 2012; 18(3):241-50.
Williams P. Introduction to food hydrocolloids. IN PHILLIPS, GO & WILLIAMS, PA (Eds) Handbook of Hydrocolloids, p 1-19. Woodhead publishing Limited; 2000.
Nguyen NH, Padil VVT, Slaveykova VI, Černík M, Ševců A. Green synthesis of metal and metal oxide nanoparticles and their effect on the unicellular alga Chlamydomonas reinhardtii. Nanoscale Res Lett. 2018; 13(1):1-13.
Sharma G, Sharma S, Kumar A, Ala'a H, Naushad M, Ghfar AA, et al. Guar gum and its composites as potential materials for diverse applications: A review. Carbohydr Polym. 2018; 199:534-45.
Kong H, Yang J, Zhang Y, Fang Y, Nishinari K, Phillips GO. Synthesis and antioxidant properties of gum arabic-stabilized selenium nanoparticles. Int J Biol Macromol. 2014; 65:155-62.
Kattumuri V, Katti K, Bhaskaran S, Boote EJ, Casteel SW, Fent GM, et al. Gum arabic as a phytochemical construct for the stabilization of gold nanoparticles: in vivo pharmacokinetics and X‐ray‐contrast‐imaging studies. Small. 2007; 3(2):333-41.
Fent GM, Casteel SW, Kim DY, Kannan R, Katti K, Chanda N, et al. Biodistribution of maltose and gum arabic hybrid gold nanoparticles after intravenous injection in juvenile swine. Nanomed: Nanotech, Biol Med. 2009; 5(2):128-35.
Shalaby T, El-Dine RSS, El-Gaber S. Green Synthesis Ofgold Nanoparticles Using Cumin Seeds and Gum Arabic: Studying Their Photothermal Efficiency. Nanosci Nanotechnol. 2015; 5(4):89-96.
Chopra M, Bernela M, Kaur P, Manuja A, Kumar B, Thakur R. Alginate/gum acacia bipolymeric nanohydrogels—Promising carrier for Zinc oxide nanoparticles. Int J Biol Macromol. 2015; 72:827-33.
Roque A, Wilson Jr O. Adsorption of gum Arabic on bioceramic nanoparticles. Mater Sci Eng C. 2008; 28(3):443-7.
Roque AC, Bicho A, Batalha IL, Cardoso AS, Hussain A. Biocompatible and bioactive gum Arabic coated iron oxide magnetic nanoparticles. J Biotechnol. 2009; 144(4):313-20.
Dong C, Cai H, Zhang X, Cao C. Synthesis and characterization of monodisperse copper nanoparticles using gum acacia. Physica E Low Dimens Syst Nanostruct. 2014; 57:12-20.
Mohan YM, Raju KM, Sambasivudu K, Singh S, Sreedhar B. Preparation of acacia‐stabilized silver nanoparticles: A green approach. J Appl Polym Sci. 2007; 106(5):3375-81.
Akele ML, Assefa AG, Alle M. Microwave-assisted green synthesis of silver nanoparticles by using gum acacia: Synthesis, characterization and catalytic activity studies. Int J Green Chem Bioprocess. 2015; 5:21-7.
Dong C, Zhang X, Cai H, Cao C. Facile and one-step synthesis of monodisperse silver nanoparticles using gum acacia in aqueous solution. J Mol Liq. 2014; 196:135-41.
Djajadisastra J, Sutriyo PP, Purnamasari P, Pujiyanto A. Antioxidant activity of gold nanoparticles using gum arabic as a stabilizing agent. Int J Pharm Pharm Sci. 2014; 6(7):462-5.
Wu C-C, Chen D-H. Facile green synthesis of gold nanoparticles with gum arabic as a stabilizing agent and reducing agent. Gold Bull. 2010; 43(4):234-40.
Baruwati B, Varma RS. High value products from waste: grape pomace extract-a three-in-one package for the synthesis of metal nanoparticles. Chem Sus Chem. 2009; 2(11):1041-4.
Chockalingam AM, Babu HKRR, Chittor R, Tiwari JP. Gum arabic modified Fe 3 O 4 nanoparticles cross linked with collagen for isolation of bacteria. J Nanobiotechnology. 2010; 8(1):1-9.
Chawla P, Kumar N, Bains A, Dhull SB, Kumar M, Kaushik R, et al. Gum arabic capped copper nanoparticles: Synthesis, characterization, and applications. Int J Biol Macromol. 2020; 146:232-42.
Zamani H, Rastegari B, Varamini M. Antioxidant and anti-cancer activity of Dunaliella salina extract and oral drug delivery potential via nano-based formulations of gum Arabic coated magnetite nanoparticles. J Drug Deliv Sci Technol. 2019; 54:101278.
Chen G, Fu Y, Niu F, Zhang H, Li X, Li X. Evaluation of the colloidal/chemical performance of core-shell nanoparticle formed by zein and gum Arabic. Colloids Surf A: Physicochem Eng Asp. 2019; 560:130-5.
Sharkawy A, Barreiro MF, Rodrigues AE. Preparation of chitosan/gum Arabic nanoparticles and their use as novel stabilizers in oil/water Pickering emulsions. Carbohydr Polym. 2019; 224:115190.
Padil VVT, Černík M. Poly (vinyl alcohol)/gum karaya electrospun plasma treated membrane for the removal of nanoparticles (Au, Ag, Pt, CuO and Fe3O4) from aqueous solutions. J Hazard Mater. 2015; 287:102-10.
Pooja D, Panyaram S, Kulhari H, Reddy B, Rachamalla SS, Sistla R. Natural polysaccharide functionalized gold nanoparticles as biocompatible drug delivery carrier. Int J Biol Macromol. 2015; 80:48-56.
Padil VVT, Černík M. Green synthesis of copper oxide nanoparticles using gum karaya as a biotemplate and their antibacterial application. Int J Nanomedicine. 2013; 8:889.
Vellora Thekkae Padil V, Nguyen NH, Ševců A, Černík M. Fabrication, characterization, and antibacterial properties of electrospun membrane composed of gum karaya, polyvinyl alcohol, and silver nanoparticles. J Nanomater. 2015; 2015.
Gangapuram BR, Bandi R, Dadigala R, Kotu GM, Guttena V. Facile green synthesis of gold nanoparticles with carboxymethyl gum karaya, selective and sensitive colorimetric detection of copper (II) ions. J Clust Sci. 2017; 28(5):2873-90.
Vellora Thekkae Padil V, Rouha M, Černík M. Hydrocolloid-stabilized magnetite for efficient removal of radioactive phosphates. Biomed Res Int. 2014; 2014 :504760.
Venkatesham M, Ayodhya D, Madhusudhan A, Kumari AS, Veerabhadram G, Mangatayaru KG. A novel green synthesis of silver nanoparticles using gum karaya: characterization, antimicrobial and catalytic activity studies. J Clust Sci. 2014; 25(2):409-22.
Kora AJ, Sashidhar R, Arunachalam J. Gum kondagogu (Cochlospermum gossypium): a template for the green synthesis and stabilization of silver nanoparticles with antibacterial application. Carbohydr Polym. 2010; 82(3):670-9.
Saravanan P, Vinod V, Sreedhar B, Sashidhar R. Gum kondagogu modified magnetic nano-adsorbent: An efficient protocol for removal of various toxic metal ions. Mater Sci Eng C. 2012; 32(3):581-6.
Vinod V, Saravanan P, Sreedhar B, Devi DK, Sashidhar R. A facile synthesis and characterization of Ag, Au and Pt nanoparticles using a natural hydrocolloid gum kondagogu (Cochlospermum gossypium). Colloids Surf B Biointerfaces. 2011; 83(2):291-8.
Rastogi L, Sashidhar R, Karunasagar D, Arunachalam J. Gum kondagogu reduced/stabilized silver nanoparticles as direct colorimetric sensor for the sensitive detection of Hg2+ in aqueous system. Talanta. 2014; 118:111-7.
Reddy GB, Madhusudhan A, Ramakrishna D, Ayodhya D, Venkatesham M, Veerabhadram G. Green chemistry approach for the synthesis of gold nanoparticles with gum kondagogu: characterization, catalytic and antibacterial activity. J Nanostructure Chem. 2015; 5(2):185-93.
Suresh Y, Annapurna S, Singh A, Chetana A, Pasha C, Bhikshamaiah G. Characterization and evaluation of anti-biofilm effect of green synthesized copper nanoparticles. Mater Today Proc. 2016; 3(6):1678-85.
Saranya KS, Vellora Thekkae Padil V, Senan C, Pilankatta R, Saranya K, George B, et al. Green synthesis of high temperature stable anatase titanium dioxide nanoparticles using Gum Kondagogu: Characterization and solar driven photocatalytic degradation of organic dye. Nanomaterials. 2018; 8(12):1002.
Padil VVT, Stuchlík M, Černík M. Plasma modified nanofibres based on gum kondagogu and their use for collection of nanoparticulate silver, gold and platinum. Carbohydr Polym. 2015; 121:468-76.
Rastogi L, Beedu SR, Kora AJ. Facile synthesis of palladium nanocatalyst using gum kondagogu (Cochlospermum gossypium): a natural biopolymer. IET nanobiotechnol. 2015; 9(6):362-7.
Venkateshaiah A, Silvestri D, Ramakrishnan RK, Wacławek S, Padil VV, Černík M, et al. Gum kondagoagu/reduced graphene oxide framed platinum nanoparticles and their catalytic role. Molecules. 2019; 24(20):3643.
Ayodhya D, Veerabhadram G. Green synthesis, characterization, photocatalytic, fluorescence and antimicrobial activities of Cochlospermum gossypium capped Ag2S nanoparticles. J Photochem Photobiol B. 2016; 157:57-69.
Rao K, Imran M, Jabri T, Ali I, Perveen S, Ahmed S, et al. Gum tragacanth stabilized green gold nanoparticles as cargos for Naringin loading: A morphological investigation through AFM. Carbohydr Polym. 2017; 174:243-52.
Kora AJ, Arunachalam J. Green fabrication of silver nanoparticles by gum tragacanth (Astragalus gummifer): a dual functional reductant and stabilizer. J Nanomater. 2012; 2012.
Ghayempour S, Montazer M, Rad MM. Tragacanth gum biopolymer as reducing and stabilizing agent in biosonosynthesis of urchin-like ZnO nanorod arrays: A low cytotoxic photocatalyst with antibacterial and antifungal properties. Carbohydr Polym. 2016; 136:232-41.
Montazer M, Keshvari A, Kahali P. Tragacanth gum/nano silver hydrogel on cotton fabric: In-situ synthesis and antibacterial properties. Carbohydr Polym. 2016; 154:257-66.
Ranjbar-Mohammadi M, Rahimdokht M, Pajootan E. Low cost hydrogels based on gum Tragacanth and TiO2 nanoparticles: characterization and RBFNN modelling of methylene blue dye removal. Int J Biol Macromol. 2019; 134:967-75.
Ghayempour S, Montazer M. Ultrasound irradiation based in-situ synthesis of star-like Tragacanth gum/zinc oxide nanoparticles on cotton fabric. Ultrason Sonochem. 2017; 34:458-65.
Darroudi M, Sabouri Z, Oskuee RK, Zak AK, Kargar H, Abd Hamid MHN. Sol–gel synthesis, characterization, and neurotoxicity effect of zinc oxide nanoparticles using gum tragacanth. Ceram Int. 2013; 39(8):9195-9.
Moradi S, Sadrjavadi K, Farhadian N, Hosseinzadeh L, Shahlaei M. Easy synthesis, characterization and cell cytotoxicity of green nano carbon dots using hydrothermal carbonization of Gum Tragacanth and chitosan bio-polymers for bioimaging. J Mol Liq. 2018; 259:284-90.
Kora AJ, Beedu SR, Jayaraman A. Size-controlled green synthesis of silver nanoparticles mediated by gum ghatti (Anogeissus latifolia) and its biological activity. Org Med Chem Lett. 2012; 2(1):1-10.
Mittal H, Mishra SB. Gum ghatti and Fe3O4 magnetic nanoparticles based nanocomposites for the effective adsorption of rhodamine B. Carbohydrate polymers. 2014; 101:1255-64.
Alam MS, Garg A, Pottoo FH, Saifullah MK, Tareq AI, Manzoor O, et al. Gum ghatti mediated, one pot green synthesis of optimized gold nanoparticles: Investigation of process-variables impact using Box-Behnken based statistical design. Int J Biol Macromol. 2017; 104:758-67.
Pandey S, Mishra SB. Catalytic reduction of p-nitrophenol by using platinum nanoparticles stabilised by guar gum. Carbohydr Polym. 2014; 113:525-31.
Dhiman N, Singh A, Verma NK, Ajaria N, Patnaik S. Statistical optimization and artificial neural network modeling for acridine orange dye degradation using in-situ synthesized polymer capped ZnO nanoparticles. J Colloid Interface Sci. 2017; 493:295-306.
Vanamudan A, Sudhakar PP. Biopolymer capped silver nanoparticles with potential for multifaceted applications. Int J Biol Macromol. 2016; 86:262-8.
Pandey S, Goswami GK, Nanda KK. Green synthesis of polysaccharide/gold nanoparticle nanocomposite: an efficient ammonia sensor. Carbohydr Polym. 2013; 94(1):229-34.
Rastogi PK, Ganesan V, Krishnamoorthi S. Palladium nanoparticles incorporated polymer-silica nanocomposite based electrochemical sensing platform for nitrobenzene detection. Electrochim Acta. 2014; 147:442-50.
Murali R, Vidhya P, Thanikaivelan P. Thermoresponsive magnetic nanoparticle–aminated guar gum hydrogel system for sustained release of doxorubicin hydrochloride. Carbohydr Polym. 2014; 110:440-5.
Pandey S, Goswami GK, Nanda KK. Green synthesis of biopolymer–silver nanoparticle nanocomposite: An optical sensor for ammonia detection. Int J Biol Macromol. 2012; 51(4):583-9.
Vanaamudan A, Sadhu M, Pamidimukkala P. Chitosan-Guar gum blend silver nanoparticle bionanocomposite with potential for catalytic degradation of dyes and catalytic reduction of nitrophenol. J Mol Liq. 2018; 271:202-8.
Souza JMT, de Araujo AR, de Carvalho AMA, Amorim AdGN, Daboit TC, de Almeida JRdS, et al. Sustainably produced cashew gum-capped zinc oxide nanoparticles show antifungal activity against Candida parapsilosis. J Clean Prod. 2020; 247:119085.
Araruna FB, de Oliveira TM, Quelemes PV, de Araujo Nobre AR, Placido A, Vasconcelos AG, et al. Antibacterial application of natural and carboxymethylated cashew gum-based silver nanoparticles produced by microwave-assisted synthesis. Carbohydr Polym. 2020; 241:115260.
Ismail NA, Amin KAM, Majid FAA, Razali MH. Gellan gum incorporating titanium dioxide nanoparticles biofilm as wound dressing: Physicochemical, mechanical, antibacterial properties and wound healing studies. Mater Sci Eng C Mater Biol Appl. 2019; 103:109770.
Zhai X, Li Z, Shi J, Huang X, Sun Z, Zhang D, et al. A colorimetric hydrogen sulfide sensor based on gellan gum-silver nanoparticles bionanocomposite for monitoring of meat spoilage in intelligent packaging. Food Chem. 2019; 290:135-43.
Alle M, Kim TH, Park SH, Lee S-H, Kim J-C. Doxorubicin-carboxymethyl xanthan gum capped gold nanoparticles: microwave synthesis, characterization, and anti-cancer activity. Carbohydr Polym. 2020; 229:115511.
Singh J, Kumar S, Dhaliwal A. Controlled release of amoxicillin and antioxidant potential of gold nanoparticles-xanthan gum/poly (Acrylic acid) biodegradable nanocomposite. J Drug Deliv Sci Technol. 2020; 55:101384.
Kora AJ, Sashidhar R, Arunachalam J. Aqueous extract of gum olibanum (Boswellia serrata): a reductant and stabilizer for the biosynthesis of antibacterial silver nanoparticles. Process Biochem. 2012; 47(10):1516-20.
Iqbal DN, Shafiq S, Khan SM, Ibrahim SM, Abubshait SA, Nazir A, et al. Novel chitosan/guar gum/PVA hydrogel: Preparation, characterization and antimicrobial activity evaluation. Int J Biol Macromol. 2020; 164:499-509.
Seku K, Gangapuram BR, Pejjai B, Hussain M, Hussaini SS, Golla N, et al. Eco-friendly synthesis of gold nanoparticles using carboxymethylated gum Cochlospermum gossypium (CMGK) and their catalytic and antibacterial applications. Chem Pap. 2019; 73(7):1695-704.
Laubach J, Joseph M, Brenza T, Gadhamshetty V, Sani RKJJocr. Exopolysaccharide and biopolymer-derived films as tools for transdermal drug delivery. J Control Release. 2021; 329:971-987.
Shirzadi-Ahodashti M, Mizwari ZM, Hashemi Z, Rajabalipour S, Ghoreishi SM, Mortazavi-Derazkola S, et al. Discovery of high antibacterial and catalytic activities of biosynthesized silver nanoparticles using C. fruticosus (CF-AgNPs) against multi-drug resistant clinical strains and hazardous pollutants. Environ Technol Innov. 2021;23:101607.
Nouri A, Yaraki MT, Lajevardi A, Rezaei Z, Ghorbanpour M, Tanzifi MJC, et al. Ultrasonic-assisted green synthesis of silver nanoparticles using Mentha aquatica leaf extract for enhanced antibacterial properties and catalytic activity. Colloids Interface Sci. Commun.2020;35:100252. 98. Cheng D, Zhang Y, Liu Y, Bai X, Ran J, Bi S, et al. Mussel-inspired synthesis of filter cotton-based AgNPs for oil/water separation, antibacterial and catalytic application. Mater Today Commun.2020;25:101467. 99. Dong Y, Zhu H, Shen Y, Zhang W, Zhang LJPo. Antibacterial activity of silver nanoparticles of different particle size against Vibrio Natriegens. PLoS One. 2019; 14(9):e0222322. 100. Lallo da Silva B, Abuçafy MP, Berbel Manaia E, Oshiro Junior JA, Chiari-Andréo BG, Pietro RCR, et al. Relationship between structure and antimicrobial activity of zinc oxide nanoparticles: An overview. Int J Nanomedicine. 2019; 14:9395-9410. 101. Mohd Yusof H, Mohamad R, Zaidan UH, Abdul Rahman NAJJoas, biotechnology. Microbial synthesis of zinc oxide nanoparticles and their potential application as an antimicrobial agent and a feed supplement in animal industry: a review. J Anim Sci Biotechnol. 2019; 10:57.
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